Prime is the complete and concentrated conditioner for both fresh and salt water. Prime removes chlorine, chloramine and ammonia. Prime converts ammonia into a safe, non-toxic form that is readily removed by the tank's biofilter. Prime may be used during tank cycling to alleviate ammonia/nitrite toxicity. Prime detoxifies nitrite and nitrate, allowing the biofilter to more efficiently remove them. Prime also promotes the production and regeneration of the natural slime coat. Prime detoxifies nitrite and nitrate, allowing the biofilter to more efficiently remove them Prime will not overactivate skimmers. Use at start-up and whenever adding or replacing water.